Here you can find all my publications, as well as talks and posters I have presented at conferences. If you’re curious to know more about a specific research topic, don’t hesitate to reach out!
Publications
First Author
- Quantitative mapping of force-pCa curves to whole-heart contraction and relaxation
Longobardi, S.; Sher, A.; Niederer, S. A.
2022
The Journal of Physiology
- In silico identification of potential calcium dynamics and sarcomere targets for recovering left ventricular function in rat heart failure with preserved ejection fraction
- Longobardi, S.; Sher, A.; Niederer, S. A.
- 2021
- PLOS Computational Biology
- In Silico Mapping of the Omecamtiv Mecarbil Effects from the Sarcomere to the Whole-Heart and Back Again
- Longobardi, S.; Sher, A.; Niederer, S. A.
- 2021
- Functional Imaging and Modeling of the Heart (FIMH 2021)
- Predicting left ventricular contractile function via Gaussian process emulation in aortic-banded rats
- Longobardi, S.; Lewalle, A.; Coveney, S.; Sjaastad, I.; Espe, E. K. S.; Louch, W. E.; Musante, C. J.; Sher, A.; Niederer, S. A.
- 2020
- Philosophical Transactions of the Royal Society A
Others
- In silico predictions of drug-induced changes in human cardiac contractility align with experimental recordings
- Trovato, C.; Longobardi, S.; Passini, E.; Beattie, K. A.; Holmes, M.; Chaudhary, K. W.; Rossman, E. I.; Rodriguez, B.
- 2025
- Frontiers in Pharmacology
- Reducing transmission in multiple settings is required to eliminate the risk of major Ebola outbreaks: a mathematical modelling study
- Evans, A.; Hart, W.; Longobardi, S.; Desikan, R.; Sher, A.; Thompson, R.
- 2025
- Journal of The Royal Society Interface
- Global Sensitivity Analysis of Thrombus Formation in the Left Atrial Appendage of Atrial Fibrillation Patients
- Smine, Z.; Melidoro, P.; Qureshi, A.; Longobardi, S.; Williams, S. E.; Aslanidi, O.; De Vecchi, A.
- 2024
- Statistical Atlases and Computational Models of the Heart (STACOM 2023)
- Cell to whole organ global sensitivity analysis on a four-chamber heart electromechanics model using Gaussian processes emulators
- Strocchi, M.; Longobardi, S.; Augustin, C. M.; Gsell, M. A. F.; Petras, A.; Rinaldi, C. A.; Vigmond, E. J.; Plank, G.; Oates, C. J.; Wilkinson, R. D.; Niederer, S. A.
- 2023
- PLOS Computational Biology
- Calibration of Cohorts of Virtual Patient Heart Models Using Bayesian History Matching
- Rodero, C.; Longobardi, S.; Augustin, C. M.; Strocchi, M.; Plank, G.; Lamata, P.; Niederer, S. A.
- 2022
- Annals of Biomedical Engineering
- Global sensitivity analysis of four chamber heart hemodynamics using surrogate models
- Karabelas, E.; Longobardi, S.; Fuchsberger, J.; Razeghi, O.; Rodero, C.; Strocchi, M.; Rajani, R.; Haase, G.; Plank, G.; Niederer, S. A.
- 2022
- IEEE Transactions on Biomedical Engineering
- Parameter Space Reduction for Four-chamber Electromechanics Simulations Using Gaussian Processes Emulators
- Strocchi, M.; Longobardi, S.; Augustin, C. M.; Gsell, M. A. F.; Vigmond, E. J.; Plank, G.; Oates, C. J.; Wilkinson, R. D.; Niederer, S. A.
- 2022
- ARGESIM Report 17 (MATHMOD 2022)
- Modelling the interaction between stem cells derived cardiomyocytes patches and host myocardium to aid non-arrhythmic engineered heart tissue design
- Fassina, D.; Costa, C. M.; Longobardi, S.; Karabelas, E.; Plank, G.; Harding, S. E.; Niederer, S. A.
- 2022
- PLOS Computational Biology
- Linking statistical shape models and simulated function in the healthy adult human heart
- Rodero, C.; Strocchi, M.; Marciniak, M.; Longobardi, S.; Whitaker, J.; O'Neill, M. D.; Gillette, K.; Augustin, C.; Plank, G.; Vigmond, E. J.; Lamata, P.; Niederer, S. A.
- 2021
- PLOS Computational Biology
- Modelling the Effects of Conductive Polymers and Stem Cells Derived Myocytes on Scarred Heart Tissue
- Fassina, D.; Costa, C. M.; Longobardi, S.; Harding, S. E.; Niederer, S. A.
- 2020
- 2020 Computing in Cardiology (CinC 2020)
- Tracking the motion of intracardiac structures aids the development of future leadless pacing systems
- Razeghi, O.; Strocchi, M.; Lee, A.; Longobardi, S.; Sidhu, B. S.; Gould, J.; Behar, J. M.; Rajani, R.; Rinaldi, C. A.; Niederer, S. A.
- 2020
- Journal of Cardiovascular Electrophysiology
- Regional diastolic dysfunction in post-infarction heart failure: role of local mechanical load and SERCA expression
- Røe, Å.; Ruud, M.; Espe, E.; Manfra, O.; Longobardi, S.; Aronsen, J.; Nordén, E.; Husebye, T.; Kolstad, T.; Cataliotti, A.; Christensen, G.; Sejersted, O.; Niederer, S. A.; Andersen, G.; Sjaastad, I.; Louch, W.
- 2018
- Cardiovascular Research
Talks
- Cardiac safety assessment using quantitative systems toxicology
- 07/03/2023
London (UK) - White City Scale Space
Cardiac Digital Twin Workshop
Contact me for full presentation
- Accelerating multi-scale Quantitative Systems Pharmacology models using a Bayesian surrogate modeling approach for quantitative translation from sub-cellular to whole-organ function: an example of evaluating Omecamtiv Mecarbil drug action in healthy rat hearts
- 08-12/11/2021
- Virtual event [Remote attendance] - Trainee Quality Abstract Awardee
- Twelfth American Conference on Pharmacometrics (ACoP12)
Contact me for full presentation
- In silico mapping of the omecamtiv mecarbil effects from the sarcomere to the whole-heart and back again
- 21-25/06/2021
- Stanford (CA, USA) - Stanford University [Remote attendance]
- The 11th biennial International Conference on Functional Imaging and Modeling of the Heart
Contact me for full presentation
- Gaussian process emulation enables a quantitative link between cellular mechanical myocardial properties and left ventricular contractile function in aortic banded rats
- 13-17/09/2020
- Rimini (Italy) - Rimini Palacongressi [Remote attendance]
- Computing in Cardiology (CinC)
Contact me for full presentation
- Predicting rat heart left ventricular function by means of Gaussian process emulation
- 09-10/09/2019
- Reading (UK) - University of Reading
- The 3rd Exchange Workshop of the UK QSP Network
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- Cardiovascular QSP modeling: virtual ventricular cell case study
- 12-16/08/2019
- Toronto (Canada) - The Fields Institute for Research in Mathematical Sciences
- Systems Modeling in the Pharmaceutical Industry: Problem Solving Workshop
Contact me for full presentation
Posters
- Quantitative mapping of Force-pCa curves to the whole heart contraction and relaxation
- 10-12/11/2021
- Virtual event [Remote attendance]
- 2021 Cardiac Physiome Workshop
- Accelerating multi-scale Quantitative Systems Pharmacology models using a Bayesian surrogate modeling approach for quantitative translation from sub-cellular to whole-organ function: an example of evaluating Omecamtiv Mecarbil drug action in healthy rat hearts
- 08-12/11/2021
- Virtual event [Remote attendance] - Trainee Quality Abstract Awardee
- Twelfth American Conference on Pharmacometrics (ACoP12)
- Quantifying contributions of cellular mechanical myocardial properties on left ventricular contractile function in aortic banded rats
- 14-19/02/2020
- San Diego (CA, USA) - San Diego Convention Center
- The 64th Annual Meeting of the Biophysical Society
- Bi-layered Gaussian process emulation of a rat heart multi-scale contraction model
- 05-07/06/2019
- Cambridge (UK) - Isaac Newton Institute for Mathematical Sciences
- Uncertainty Quantification for Cardiac Models
- A virtual drug development for the recovery of a heart failing rat with preserved ejection fraction condition induced via transverse aortic constriction
- 04-07/09/2018
- Berlin (Germany) - Max Delbrück Center for Molecular Medicine
- The Heart by Numbers: Integration Theory, Computation and Experiment to advance Cardiology